Saturday, April 14, 2018

AHA Study Looks at Vegetable Intake Impact on Heart Disease Risk


An experienced cardiologist and educator, Dr. Sanjiv M. Narayan specializes in researching and treating heart arrhythmia. A professor of medicine at Stanford University, Dr. Sanjiv Narayan belongs to the American Heart Association. 

A recent study in the Journal of the American Heart Association showed that women who eat more vegetables have a decreased thickness in their artery walls. The foods used in the study were broccoli, cabbage, cauliflower, and other cruciferous vegetables. 

Researchers found that arterial wall thickness decreased by 0.05 millimeters in those who had an increased intake of cruciferous vegetables. Each 0.1-millimeter decrease in thickness can equate to a 10- to 18-percent smaller risk of a stroke or heart attack.

Though the study shows promise, researchers were quick to say that, without further research, they can’t confirm a direct relationship between the increased vegetable intake and the arterial wall thickness.

Sunday, April 1, 2018

New Gene Therapy Approach to Treating Atrial Fibrillation


An accomplished cardiologist, Dr. Sanjiv M. Narayan has been granted National Institutes of Health funding to undertake basic research in understudied areas of human heart rhythm disorders (arrhythmia). Technology focused, Dr. Sanjiv M. Narayan was successful in developing a pioneering system that addressed patient atrial-fibrillation-care needs. 

Atrial fibrillation (AF) is the most prevalent type of arrhythmia. Its treatment focuses on restoring the normal rhythm of the heart, and encompasses anticoagulant drugs that not all patients respond to as well as electric shocks that require patient hospitalization. 

A recent study at the Leiden University Medical Centre in the Netherlands examined the potential use of genetically modified cells in enabling the heart to terminate AF on its own.

Employing a gene painting process, the right atrium of hearts in adult rats were genetically modified such that they expressed light-sensitive ion channels. Shining a light on the atrium for one second resulted in an opening of these light-sensitive ion channels in rats with induced atrial fibrillation. This resulted in a restoration of normal heart rhythm and termination of the atrial fibrillation.

As described by the researchers, this technique has the potential to be used for atrial fibrillation patients, in tandem with an implantable LED device, such that the heart’s normal rhythm could be maintained in a continuous and pain-free manner.