Sunday, November 11, 2018

Examining Ablation in Concert with PVI for Treating AF


An accomplished educator and researcher, Dr. Sanjiv M. Narayan serves as a professor of medicine and the director of the Stanford Arrhythmia Center. Dr. Sanjiv Narayan has studied numerous aspects of atrial fibrillation (AF), including ablation of AF drivers and its clinical implications. 

Pulmonary vein isolation, or PVI, is a procedure used to stop abnormal electrical signals in the heart that cause atrial fibrillation. PVI as a treatment for AF has been met with less-than-optimal outcomes, however, and the impact of adding lesion sets--additional surgical treatments for AF--has yet to be adequately explored. 

Some recent studies suggest that AF driver ablation, through which doctors intentionally scar tissues by sending irregular electric signals to the heart, may be a preferable treatment option to couple with PVI, but others suggest otherwise. In an effort to gain a clearer perspective, Dr. Narayan and a team of researchers conducted a comprehensive meta-analysis of all the literature on the subject.

The research team found that supplementing PVI treatment with AF driver ablation may be an option to improve patient outcomes, with several studies supporting this approach using several techniques. They suggest randomized clinical trials conducted at different research centers to study the treatment in further detail.