Tuesday, May 19, 2020

T Wave Alternans Can Help Detect Potential Heart Defects


Board-certified in Clinical Cardiac Electrophysiology, Dr Sanjiv Narayan serves as the professor of cardiovascular medicine at the Stanford University Medical Center. Sanjiv Narayan, PhD, has written several medical papers, including the role of alternating repolarization in causing rhythm problems.

Repolarization changes can cause arrhythmias. This was previously part of the surface electrocardiogram phenomenon of "T wave (repolarization) alternans" and is now increasingly noticed in the atrium. This is detectable using clinical tools but also several research tools. These are being explored to better understand the heart rhythm problem, and also to improve therapy of patients.

Ventricular arrhythmia can cause asymptomatic heart failure, leading to death without prior notice. In some cases, however, ventricular arrhythmia may present with less potent lethal complications such as ventricular fibrillation and ventricular tachycardia. Current treatments for ventricular arrhythmia involve device therapy and ablation. These can be effective, but it is difficult to identify which patients may benefit from each form of therapy.