Friday, July 27, 2018

Dipole Density Mapping Validated in Atrial Fibrillation Cases


Dr. Sanjiv M. Narayan, a respected presence in the Southern and Northern California cardiology sphere, developed pioneering atrial fibrillation (AF) care techniques which are now supported other studies. Sanjiv Narayan’s research findings have been validated in the 2017 paper "Dipole Density Mapping of Atrial Fibrillation” (European Heart Journal).

With primary researcher Cambridge University professor Andrew Grace serving on the Acutus Medical Scientific Advisory Board, the study involved a new Acutus Medical mapping system that addresses the complexity of AF patient-specific arrhythmia. Unfortunately, the present care standard for persistent AF is the same as for paroxysmal AF, although the outcomes are significantly inferior for patients with the persistent form of the condition. 

An innovative diagnostic tool, the AcQMap System enables the cardiac tissues that cause arrhythmias to be located and precisely targeted, in the process minimizing the need for redundant therapies. The early clinical results reveal that this approach elevates the accuracy of left atrial reconstruction, without elevated patient risk, through successfully mapping unstable and stable atrial arrhythmias. 

As described by Dr. Grace, the AcQMap’s advanced performance is likely to present an improved pathway for treating persistent AF, as compared with 3D voltage-based mapping systems.

Sunday, July 22, 2018

Getting the Most Out of Time in the Pool


Sanjiv M. Narayan has, for nearly three decades, been part of the medical field, building an extensive body of research regarding heart rhythm irregularities. During his spare time, Sanjiv Narayan enjoys staying physically fit and considers swimming and skateboarding among his favorite athletic activities.

Swimming can be an intensive workout, but getting what one wants out of a swim can be challenging. With a little preparation, however, swimmers can meet their fitness goals and not get bored.

Different strokes train different muscle groups and stress different parts of the body. The breaststroke, for instance, improves the leg muscles, while crawl is great for stamina and cardiovascular health. Those looking for a solid core can use the butterfly, while those who want better posture can try the breaststroke.

Those who really want to focus in on individual trouble areas can consider pool toys and other assistive devices. A hand paddle or float can help isolate individual body parts. Similarly, a swim parachute can create drag, improving both speed and stamina. By using these devices, swimmers can get the exact workout their bodies need.

Saturday, May 26, 2018

Electrophysiology - What to Expect


Dr. Sanjiv M. Narayan serves as director of the atrial fibrillation and electrophysiology research programs at Stanford University. Dr. Sanjiv Narayan has shared his work through such publications as Circulation, Journal of the American College of Cardiology, Journal of Cardiovascular Electrophysiology which from 2002 to 2017 have published his team's findings on the mapping of irregular heart rhythms.

Electrophysiology (EP) is a category of testing that evaluates the electrical activity of the heart and the patterns that it follows. Often used to evaluate the source of an arrhythmia, or regular heartbeat, it can assist in the development of a course of treatment.

The patient visits an EP or catheterization (cath) lab, where he or she receives a sedative and local anesthetic. The doctor will then make a small incision in the groin, arm, or neck, to thread a small tube known as a sheath into a particular vein or artery. This sheath contains a series of specialized catheters, which the physician will guide toward the heart.

Once the catheters are in place, the physician will send electrical signals into the heart to safely reproduce the irregular heartbeat. The catheters will record the heartbeat in a way that maps the arrhythmia. This allows the physician to identify the source of the abnormality.

The process usually takes between one and four hours. When it is finished, the doctor will remove the catheters. Recovery time, which includes pressure and elevation of the surgical site, usually lasts for one to three hours.

Tuesday, May 15, 2018

Study on Localized Atrial Fibrillation (AF) That Ends Persistent AF


A professor of medicine at Stanford University, Dr. Sanjiv M. Narayan has led basic human heart rhythm disorder research in areas that were little studied. Extensively published in his field, Dr. Sanjiv M. Narayan coauthored “Identification and Characterization of Sites Where Persistent Atrial Fibrillation Is Terminated by Localized Ablation” (Circulation Arrhythmia Electrophysiology, 2018).

With atrial fibrillation (AF) characterized by irregularity of heartbeat and presenting a danger of blood-clot-related stroke, the study sought to increase knowledge of how persistent AF terminates when localized ablation is undertaken. Cardiac ablation involves the elimination or scarring of the heart tissue responsible for allowing incorrect electrical signals that activate the heart muscles in a way that results in abnormal heart rhythm.

A study hypothesis was that those sites at which localized ablation eliminates persistent AF have characteristics that can be identified through activation mapping when AF occurs. With 57 patients taking part in the study, complex analysis was undertaken that revealed repetitive rotational or focal activity patterns occurring at all sites in which AF termination occurred. Not all methods were equally effective at identifying these sites. The mechanism through which local ablation has this effect is described as needing further research.

Saturday, April 14, 2018

AHA Study Looks at Vegetable Intake Impact on Heart Disease Risk


An experienced cardiologist and educator, Dr. Sanjiv M. Narayan specializes in researching and treating heart arrhythmia. A professor of medicine at Stanford University, Dr. Sanjiv Narayan belongs to the American Heart Association. 

A recent study in the Journal of the American Heart Association showed that women who eat more vegetables have a decreased thickness in their artery walls. The foods used in the study were broccoli, cabbage, cauliflower, and other cruciferous vegetables. 

Researchers found that arterial wall thickness decreased by 0.05 millimeters in those who had an increased intake of cruciferous vegetables. Each 0.1-millimeter decrease in thickness can equate to a 10- to 18-percent smaller risk of a stroke or heart attack.

Though the study shows promise, researchers were quick to say that, without further research, they can’t confirm a direct relationship between the increased vegetable intake and the arterial wall thickness.

Sunday, April 1, 2018

New Gene Therapy Approach to Treating Atrial Fibrillation


An accomplished cardiologist, Dr. Sanjiv M. Narayan has been granted National Institutes of Health funding to undertake basic research in understudied areas of human heart rhythm disorders (arrhythmia). Technology focused, Dr. Sanjiv M. Narayan was successful in developing a pioneering system that addressed patient atrial-fibrillation-care needs. 

Atrial fibrillation (AF) is the most prevalent type of arrhythmia. Its treatment focuses on restoring the normal rhythm of the heart, and encompasses anticoagulant drugs that not all patients respond to as well as electric shocks that require patient hospitalization. 

A recent study at the Leiden University Medical Centre in the Netherlands examined the potential use of genetically modified cells in enabling the heart to terminate AF on its own.

Employing a gene painting process, the right atrium of hearts in adult rats were genetically modified such that they expressed light-sensitive ion channels. Shining a light on the atrium for one second resulted in an opening of these light-sensitive ion channels in rats with induced atrial fibrillation. This resulted in a restoration of normal heart rhythm and termination of the atrial fibrillation.

As described by the researchers, this technique has the potential to be used for atrial fibrillation patients, in tandem with an implantable LED device, such that the heart’s normal rhythm could be maintained in a continuous and pain-free manner.

Saturday, March 17, 2018

Study Links Sleep-Disordered Breathing and Heart Failure Risks


Dr. Sanjiv M. Narayan is a pioneering cardiologist who, in his career, has developed novel strategies for treating atrial fibrillation and improving patient outcomes. Among Dr. Sanjiv M. Narayan’s other areas of interest is sleep-disordered breathing, which is linked to conditions such as the stiffening of arterial walls and the increased risk of heart failure. 

The results of a recent study by researchers at Fukushima Medical University, published in ESC Heart Failure, a journal of the European Society of Cardiology, reinforced this link. The study showed a positive correlation between the severity of sleep-disordered breathing and arterial stiffness. 

The findings suggest that treatments of obstructive sleep apnea through the use of continuous positive airway pressure (CPAP) devices and other technologies may have a positive impact on patient prognosis. 

As study coauthor Dr. Akiomi Yoshihisa described it, the effective use of CPAP may extend beyond the hypertension that it is currently confirmed to address and enable recovery among patients at risk of preserved ejection-fraction-linked heart failure.

Wednesday, September 13, 2017

Wearables Help Protect the Health of Athletes on the Field


Dr. Sanjiv M. Narayan is a Southern California cardiologist who has developed innovative atrial fibrillation care modalities that were acquired by Abbott Laboratories. With a strong interest in technologies that make life easier and more convenient, Dr. Sanjiv Narayan follows developments in the wearables sphere. 

Athletics presents one of the most dynamic areas of growth in the wearables market, as amateur and pro athletes seek to monitor health and enhance their competitive edge. A major trend is in the development of smart fabrics that gather essential performance data without adding weight. 

Information gathered includes critical aspects of body function, such as exhaustion and stress levels. With Sudden Adult Death Syndrome a rising concern within the professional sports sphere, these technologies promise to identify potential overtraining issues before they reach critical, health-adverse levels. 

Examples of such so-called preventive health sports technologies include the RFID Zebra player-tracking system, which was introduced throughout the NFL in 2016. In addition, Major League Baseball recently approved a Motus Global compression sleeve used for tracking pitcher’s arm workloads and a Zephyr heart-monitoring strap.

Saturday, September 2, 2017

ACC to Work with Chinese Health Professionals


A professor of medicine at Stanford University, Dr. Sanjiv M. Narayan focuses on research and patient care related to heart arrhythmias and serves as director of the Electrophysiology Training Program and co-director of the Electrophysiology Service. Apart from his work at Stanford, Dr. Sanjiv Narayan is a Fellow of the American College of Cardiology (ACC). 

Earlier this year, the ACC entered into a partnership with several Chinese hospitals that will see doctors in the central and eastern provinces of the country receive training and education on how to prevent heart disease, as well as how to diagnose and effectively treat heart-related conditions. Most of the information will be delivered in lecture settings and other educational forums. 

The educational effort is sponsored by the Edwards Lifesciences Foundation’s Every Heartbeat Matters and will target Kunming in Yunnan Province, Wuhan in Hubei Province, and Fuzhou in Fujian Province. Educators also will develop patient-related materials to help raise awareness about heart disease among the general population.

Saturday, August 12, 2017

Fitbit Working on Sleep Apnea Wearable Device


A professor of medicine at Stanford University, Dr. Sanjiv M. Narayan is also the co-founder and co-director of the school’s Arrhythmia Center, which works to develop innovative bioengineered arrhythmia medicine. Outside of his professional life, Dr. Sanjiv Narayan maintains a personal interest in wearable technology like Fitbit. 

Fitbit, maker of the fitness tracker of the same name, is currently working on a new device that will help track and recognize sleep apnea. Sleep apnea, a disorder that inhibits proper breathing during sleep, affects 18 million Americans.

The technology, which Fitbit hopes to have finished by 2018, uses a small light to shine through the wearer’s skin to detect the precise color of the blood, which indicates how well-oxygenated it is. For those undiagnosed with sleep apnea, the technology can help determine if they have the disorder, and if or when they should consult a doctor. For those who have already been diagnosed, the wearable can help evaluate the effectiveness of apnea treatment. 

Fitbit, already testing prototypes in sleep labs, hopes to enter the medical technology sector to compete with their biggest wearable tech rival, Apple. Provided the medical community accepts the new technology, Fitbit will still have to get approval from the FDA and similar regulatory agencies in other countries.

Tuesday, August 1, 2017

A Wearable Device that Monitors Glucose Levels


Dr. Sanjiv M. Narayan serves as a professor of medicine at Stanford University where he conducts research focusing on bioengineering solutions to clinical problems. Following his work as the Director of Electrophysiology at the Veterans Affairs Medical Center in San Diego, California, Dr. Sanjiv Narayan developed an innovative therapy called FIRM for people suffering from heart rhythm disorders. In addition, Dr. Narayan has developed an interest in wearable devices that can improve overall health.

An innovative solution to cumbersome and invasive glucose monitoring was introduced at the Consumer Electronics Show in early 2017. The K’Watch Glucose monitor is a wrist worn tracking device that eliminates the need for finger pricks and expensive test strips. The first of its kind, the K’Watch is a wearable device that syncs the data it gathers with iOS or Android apps.

Manufactured by PKVitality, the K’Watch inserts two microneedles into the outer layers of skin to absorb interstitial fluid which gathers around tissue cells. The interstitial fluid sample is then delivered to an internal biosensor called SkinTaste where glucose levels are analyzed. 

The technology in the K’Watch will help people who suffer from diabetes continually monitor their glucose levels as suggested by their physicians. PKVitality continues to finalize manufacturing details and is hoping to complete the medical certification process within the year, ultimately releasing the K’Watch to the public in 2018.

Wednesday, April 12, 2017

New Research on Sleep Apnea and Developing Brains




Licensed to practice cardiology in California and Missouri, Dr. Sanjiv Narayan is the founder of a technology development firm that he sold to Abbott Laboratories. In acquiring the startup, Abbott gained leading-edge atrial fibrillation treatment modalities with the potential to improve care for patients worldwide. Dr. Sanjiv Narayan has a strong interest in diverse areas of medicine, including sleep apnea.

A condition related to relaxation of the throat muscles during the night, which is also related to atrial fibrillation, sleep apnea causes airway obstruction and brief halts to breathing. Once the brain becomes aware of danger, it sends out signals that wake up the person, and the throat muscles contract and temporarily resolve the problem. Such interruptions can occur as many as 30 times a night, leading to chronic sleep issues.

While little research has been undertaken on sleep apnea and the developing brain, the condition affects approximately 5 percent of children. A recent study pairing University of Chicago and University of California research teams and using brain scan analysis suggests that sleep apnea in children may result in gray matter losses spanning diverse regions of the brain. The next step is described as being one of exploring how these losses may be related to cognitive defects.

Wednesday, March 1, 2017

More People Living with Heart Failure


Dr. Sanjiv Narayan is the founder of Topera, a medical technology company that was acquired by Abbott Laboratories in 2014. Dr. Sanjiv Narayan has served in several roles at Stanford University, including director of the Atrial Fibrillation Program. He has also continued to maintain membership in the American Heart Association.

Through its 2017 Heart Disease and Stroke Statistics Update, the American Heart Association recently released data that shows more Americans are living with heart failure compared to previous years. Over a three-year period from 2011 to 2014, the number of those living with heart failure increased by approximately 800,000 from 5.7 million to 6.5 million, with those figures expected to increase by 46 percent over the next 15 years. 

One reason experts believe more people are living with heart failure has to do with advancements in medical science. Individuals who survive heart attacks are at an increased risk of heart failure later in life, and increasingly effective treatments allow more people to survive these cardiac events than in previous years. People living to older ages is also a contributing factor.